2-Methylindole, 98+%

Description

CAS: 95-20-5 | C9H9N | 131.178 g/mol

2-Methylindole is used as a reactant for regioselective synthesis of oxopyrrolidine analogs via iodine-catalyzed Markovnikov addition reaction, Friedel-Crafts alkylation reactions, preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators, Michael addition reactions and in synthesis of cyclooxygenase-1 (COX-1)/cyclooxygenase-2 (COX-2) inhibitors.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-Methylindole is used as a reactant for regioselective synthesis of oxopyrrolidine analogs via iodine-catalyzed Markovnikov addition reaction, Friedel-Crafts alkylation reactions, preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators, Michael addition reactions and in synthesis of cyclooxygenase-1 (COX-1)/cyclooxygenase-2 (COX-2) inhibitors.

Solubility
Insoluble in water.

Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents. It is sensitive to light.

Specifications

Chemical Identifiers

• CAS: 95-20-5
• Molecular Formula: C9H9N
• Molecular Weight (g/mol): 131.178
• MDL Number: MFCD00005616
• InChI Key: BHNHHSOHWZKFOX-UHFFFAOYSA-N
• Synonym: 2-methylindole, 1h-indole, 2-methyl, indole, 2-methyl, 2-methyl indole, unii-i7cn58827i, 2-methylindol, methylketole, methyl indole, 2-methyl-indole, pubchem7504
• PubChem CID: 7224
• ChEBI: CHEBI:49402
• IUPAC Name: 2-methyl-1H-indole
• SMILES: CC1=CC2=CC=CC=C2N1

• Melting Point: 56°C to 60°C
• Density: 1.07
• Boiling Point: 272°C to 273°C
• Flash Point: 141°C (285°F)
• Quantity: 50 g
• Beilstein: 109781
• Sensitivity: Air and light sensitive
• Solubility Information: Insoluble in water.
• Formula Weight: 131.18
• Percent Purity: ≥98%
• Chemical Name or Material: 2-Methylindole

Safety and Handling

Hazard Category	H302-H315-H319-H335
Hazard Statement	GHS H Statement H301 Toxic if swallowed.
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
DOTInformation	Hazard Class: 9; Packaging Group: III
EINECSNumber	202-398-3
RTECSNumber	NM0345000
TSCA	Yes
Recommended Storage	Ambient temperatures; Store under Argon

SDS

RUO – Research Use Only