Learn More
Eurofins Discoverx 2-(methylthio)-ADP, 5 mg. (92-1177)
Supplier: Eurofins Discoverx 921177
2-(Methylthio)adenosine 5′-diphosphate (2-methylthio-ADP) induces platelet aggregation and inhibits cAMP accumulation in platelets in-vitro. It's 3-5 times more active than ADP as an aggregating agent, and 150-200 times more active as a cAMP accumulation inhibitor. Potent agonist of the P2Y1, P2Y12, and P2Y13 purinoceptors (pEC50=8.29 and 9.05 nM for P2Y1 and P2Y12, and EC50=19 nM for P2Y13). These highly purified, pre-validated control ligands have been used to qualify our InCELL Hunter, PathHunter and cAMP Hunter cell lines as well as our Assay Ready Kits. Ligands are conveniently supplied with a recommended reconstitution buffer. For detailed information and product-specific datasheet, visit www.discoverx.com/ligands.
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.