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Medchemexpress LLC 2-naphthalenecarboxamide, N-(4-chlorophenyl)-3-hydroxy- | 92-78-4 | MFCD00021639 | 98.0% | 297.74 g/mol | C17H12ClNO2 | 1 G
SDP

Supplier:  Medchemexpress LLC HY1040681G

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Naphthol AS-E is a small-molecule inhibitor that disrupts the KIX-KID interaction by binding the KIX domain of CBP. It blocks CREB-mediated KIX-KID binding with reported IC50 ≈ 2.26 μM and Kd ≈ 8.6 μM, and shows cellular activity in multiple cancer cell lines. The compound is supplied as a solid with reported purity ≥98% for research use.

  • Inhibits KIX-KID interaction with low micromolar potency.
  • Directly binds CBP KIX domain (Kd 8.6 μM).
  • Blocks KIX-KID interaction (IC50 2.26 μM).
  • Demonstrated cellular activity in cancer cell lines.
  • High reported purity suitable for biochemical assays.

Catalog No. 50-002-42562


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