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Apexbio Technology LLC 2-NBDG(Synonyms: 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose, Fluorescent glucose analogue), 10mg, CAS: 186689-07-6.
Supplier: Apexbio Technology LLC B603510
2-NBDG (CAS 186689-07-6) is a fluorescently labeled derivative of 2-deoxyglucose employed as a tracer for cellular glucose uptake Upon entering the cell via glucose transporter proteins 2-NBDG undergoes phosphorylation by hexokinase resulting in intracellular retention Due to its fluorescent properties uptake of 2-NBDG can be conveniently analyzed through methods like flow cytometry fluorescence microscopy or microplate assays This compound enables the monitoring of glucose metabolism dynamics in various cell types such as HepG2 L6 myocytes MCF-7 cancer cells and astrocytes as well as in disease models including diabetes epilepsy hyperglycemia and tumor xenografts
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