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Apexbio Technology LLC 2'-O-Methyl-GTP 50ul (100 mM)

Supplier: Apexbio Technology LLC B79700.05
2 -O-Methyl-GTP is a chemically modified nucleotide analog in which a methyl group is introduced at the 2 -hydroxyl position of guanosine triphosphate (GTP) Due to this structural modification it competes directly with standard GTP molecules during RNA polymerization and acts as a chain terminator thereby inhibiting the process of RNA synthesis Researchers utilize 2 -O-Methyl-GTP predominantly in studies investigating RNA polymerase enzymatic fidelity transcription regulation and RNA-mediated mechanisms It serves as a molecular tool in experimental setups aiming to elucidate RNA synthesis pathways probe enzyme active site specificity or suppress targeted RNA transcription reactions in vitro
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