Medchemexpress LLC 2'-O-Methylguanosine | 2140-71-8 | 99.8% | 297.27 | 100 MG

Supplier:  Medchemexpress LLC HYW013260100MG

2'-O-Methylguanosine is a modified nucleoside produced in tRNAs by the action of tRNA guanosine-2'-O-methyltransferase. It results in apoptotic changes of cells and can induce apoptosis in Molt4 cells. It also inhibits the activity of RNA-dependent RNA polymerase after the incorporation of nucleotides, thereby protecting coronavirus RNA from degradation by host nucleases.

• Modified nucleoside.
• Apoptosis inducing nucleoside (AIN).
• Can be isolated from the culture supernatant of CD57⁺HLA-DRbright natural suppressor cell (57.DR-NS).
• Induces DNA fragmentation and apoptosis in Molt4 cells.
• Inhibits RNA-dependent RNA polymerase activity.
• Protects coronavirus RNA from degradation.

Catalog No. 50-004-54149