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Medchemexpress LLC 2'-O-Methylguanosine | 2140-71-8 | 99.8% | 297.27 | 250 MG
Supplier: Medchemexpress LLC 250MGHYW013260
2'-O-Methylguanosine is a modified nucleoside produced in tRNAs by the action of tRNA guanosine-2'-O-methyltransferase. It results in apoptotic changes of cells. For research use only; not sold to patients.
- Modified nucleoside produced in tRNAs
- Induces apoptotic changes in cells
- Can be isolated from the culture supernatant of CD57⁺HLA-DRbright natural suppressor cell (57.DR-NS)
- Induces apoptosis in Molt4 cells at 7 μg/mL for 72 h
- Inhibits the activity of RNA-dependent RNA polymerase after nucleotide incorporation by hindering translocation
- Protects coronavirus RNA from degradation by host nucleases
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