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Medchemexpress LLC 2′-O-Methyluridine-d3 | 2140-76-3 | 99.2% | 261.25 | 5 MG
SDP

Catalog No. 5000453735
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2′-O-Methyluridine-d3 is a deuterium-labeled version of 2′-O-Methyluridine. The unlabeled compound is a modified nucleoside found in *T. thermophile* tRNA. It can be incorporated into siRNA to target the gene encoding apolipoprotein B, which leads to a decrease in ApoB protein levels in HepG2 cells and prevents IFN-α production in isolated human PBMCs. Decreased levels of 2'-O-Methyluridine in serum have been observed in patients with breast cancer.

  • Can be used as a tracer.
  • Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
  • Deuterium substitution can affect the pharmacokinetic and metabolic profiles of drugs.
  • Stable heavy isotope of hydrogen.

Catalog No. 50-004-53735 Supplier Medchemexpress LLC Supplier No. HYW011824S5MG
May include imposed supplier surcharges.
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2′-O-Methyluridine-d3 is a deuterium-labeled version of 2′-O-Methyluridine. The unlabeled compound is a modified nucleoside found in *T. thermophile* tRNA. It can be incorporated into siRNA to target the gene encoding apolipoprotein B, which leads to a decrease in ApoB protein levels in HepG2 cells and prevents IFN-α production in isolated human PBMCs. Decreased levels of 2'-O-Methyluridine in serum have been observed in patients with breast cancer.

  • Can be used as a tracer.
  • Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
  • Deuterium substitution can affect the pharmacokinetic and metabolic profiles of drugs.
  • Stable heavy isotope of hydrogen.

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