Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC 2-propen-1-one, 1-(2-hydroxyphenyl)-3-phenyl- | 1214-47-7 | 97.45% | 224.25 | 100 MG
Supplier: Medchemexpress LLC HYW012349100MG
2′-Hydroxychalcone is a hydroxyl derivative of chalcones with anticancer activities. It inhibits the NF-κB pathway and induces autophagy and apoptosis in breast cancer cells. It also demonstrates antifungal activity against complex Paracoccidioides spp. This product is for research use only.
- Suppresses cell viability in a dose-dependent manner
- Promotes autophagy vesicle accumulation
- Induces autophagy-dependent apoptosis in breast cancer cells
- Significantly reduces p-IκB and p-NF-κBp65 expression
- Elevates p-ERK and p-JNK levels
- Increases intracellular ROS levels
- Triggers endoplasmic reticulum stress (ERS)
- Exhibits in vivo antitumor effect
- Suppresses tumor growth and metastasis in vivo
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?