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Medchemexpress LLC 2-Propenamide, N-[2-[(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]phenyl]- | 2513289-74-0 | C15H12ClN5O | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY152185

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BSJ-04-122 is a covalent MKK4/7 dual inhibitor that inhibits MKK4 and MKK7 with IC50 values of 4 nM and 181 nM, respectively. This compound is suitable for cancer research.

  • Inhibits MKK4 with an IC50 of 4 nM
  • Inhibits MKK7 with an IC50 of 181 nM
  • Induces robust reduction of JNK phosphorylation at concentrations of 1, 5, and 10 μM within 6 hours
  • Shows enhanced antiproliferative effects when combined with JNK-IN-8

Catalog No. 50-003-74723


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