Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000365548

Medchemexpress LLC 2-Pyrazinecarboxamide, 3-amino-6-[4-(methylsulfonyl)phenyl]-N-phenyl- | 1232410-49-9 | 99.7% | 368.41 | 10 MG
SDP

Supplier:  Medchemexpress LLC 10MGHY14731

Encompass_Preferred

VE-821 is a potent ATP-competitive inhibitor of ATR with Ki/IC50 of 13 nM/26 nM. It demonstrates excellent selectivity for ATR with minimal cross-reactivity against related PIKKs such as ATM, DNA-PK, mTOR, and PI3Kγ. This compound enhances the sensitivity of pancreatic cancer cells to radiation and Gemcitabine, and inhibits radiation-induced G2/M arrest in cancer cells.

  • Potent ATP-competitive inhibitor of ATR
  • Excellent selectivity for ATR with minimal cross-reactivity
  • Enhances sensitivity of pancreatic cancer cells to radiation and Gemcitabine
  • Inhibits radiation-induced G2/M arrest in cancer cells
  • Inhibits phosphorylation of Chk1 (Ser 345)

Catalog No. 50-003-65548


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.