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Medchemexpress LLC 2-Pyridinecarboxylic acid, 3-mercapto-, hydrochloride (1:1) | 320386-54-7 | 96.4% | 25 MG
Supplier: Medchemexpress LLC 25MGHY128923
SKF-34288 (3-Mercaptopicolinic acid) hydrochloride is an orally active phosphoenolpyruvate carboxykinase (PEPCK) inhibitor with a Ki of 2-9 μM. It functions as a potent hypoglycemic agent by inhibiting glucose synthesis, and also inhibits Asn metabolism, leading to an increase in amino acids and amides.
- Orally active PEPCK inhibitor (Ki: 2-9 μM)
- Potent hypoglycemic agent
- Inhibits glucose synthesis
- Inhibits Asn metabolism
- Increases amino acids and amides
- Inhibits C2C12 cell proliferation in vitro
- Induces myogenic differentiation of C2C12 cells
- Reduces mRNA expression of Pck2 and genes associated with serine biosynthesis
- Reduces blood glucose in starved rats in vivo
- Neutralizes Salbutamol-mediated hyperglycemia in rabbits
- Reduces Pyruvate-induced blood glucose level in rats
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