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Medchemexpress LLC 2-Pyrrolidinone, 5-[(3S)-3-hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5-yl)hexyl]- | 346673-06-1 | 98.3% | 383.49 | 50 MG

Supplier: Medchemexpress LLC HY108557500UG
TCS 2510 is a selective EP4 agonist and can be used for the research of metabolic diseases. It stimulates glucagon-like peptide 1 and 2 secretion, activates the Gas signaling pathway, and increases Gcg mRNA expression levels. In vivo studies show it elevates plasma glucagon-like peptide 1 and 2 levels in mice.
- Stimulates glucagon-like peptide 1 secretion.
- Activates the Gas signaling pathway.
- Increases Gcg mRNA expression levels.
- Produces a concentration-dependent increase in cAMP levels in GLUTag cells.
- Decreases cell impedance in GLUTag cells.
- Produces a concentration-dependent increase in glucagon-like peptide 2 secretion.
- Elevates plasma glucagon-like peptide 1 levels in fasted mice.
- Increases plasma glucagon-like peptide 2 levels in mice.
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