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Medchemexpress LLC 2-thiophenecarboxamide, 3-[(4-chlorophenyl)methoxy]-N-[(1S)-1-phenylethyl]- | 1203680-76-5 | 100.0% | 371.88 | 50MG
SDP

Supplier:  Medchemexpress LLC HY1868650MG

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AS1949490 is a potent, orally active, selective SHIP2 phosphatase inhibitor. It exhibits IC50 values of 0.34 μM for Mouse SHIP2, 0.62 μM for Human SHIP2, 13 μM for Human SHIP1, and >50 μM for Human PTEN, Human synaptojanin, and Human myotubularin. This compound enhances the phosphorylation of Akt, glucose consumption, and glucose uptake, and it activates intracellular insulin signaling pathways.

  • Potent, orally active, selective SHIP2 phosphatase inhibitor.
  • Increases Akt phosphorylation.
  • Enhances glucose consumption and uptake.
  • Activates intracellular insulin signaling pathways.
  • Suitable for diabetes research.

Catalog No. 50-003-87926


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