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Medchemexpress LLC 2-Thiophenemethanamine, N-[(4-chloro-2-methylphenyl)methyl]-N-[(4-chlorophenyl)methyl]-5-nitro- (hydrochloride) | 98.5% | 457.80 | 10 MG
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Supplier:  Medchemexpress LLC HY117147A10MG

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GSK2945 hydrochloride is a tertiary amine, and is a highly specific Rev-erbα/REV-ERBα (mouse/human reverse erythroblastosis virus α) antagonist with EC50s of 21.5 μM and 20.8 μM, respectively. GSK2945 hydrochloride enhances cholesterol 7α-hydroxylase (CYP7A1) level and cholesterol metabolism. It is intended for research use only and is not sold to patients.

  • Highly specific Rev-erbα/REV-ERBα antagonist
  • Enhances cholesterol 7α-hydroxylase (CYP7A1) level
  • Promotes cholesterol metabolism
  • Increases the transcriptional activity of Rev-erbα
  • Upregulates Lrh-1/LRH-1 mRNA and protein

Catalog No. 50-004-36961


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