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Cayman Chemical 2AmIno3methylImIdazo4 5f 50mg
Supplier: Cayman Chemical 2185350 MG
A food-derived carcinogen; metabolized by CYP1A2 and conjugated by N-acetyltransferase or sulfotransferase to a metabolite that reacts with DNA to form adducts; induces formation of single-base substitutions and exon deletions and increases cell death in vitro; increases incidence of squamous cell hyperplasias in the stomach of p53 knockout mice; increases hepatocellular lesions in female mice regardless of p53 status
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