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Medchemexpress LLC (2E)-1-(4-acetyl-1-piperazinyl)-3-[4-[[2-(1-methylethyl)phenyl]thio]-3-nitrophenyl]-2-propen-1-one | 280749-17-9 | MFCD19690958 | 99.3% | 453.55 g·mol⁻¹ | C24H27N3O4S | 25 MG
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Supplier:  Medchemexpress LLC HY10758725MG

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A 286982 is a small-molecule, allosteric inhibitor of leukocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1 (ICAM-1) interaction. It blocks LFA-1/ICAM-1 binding and LFA-1-mediated cellular adhesion and is used as a tool compound in in vitro binding and cell adhesion assays.

  • Potent allosteric inhibition of LFA-1/ICAM-1 (IC50 44 nM binding; 35 nM adhesion).
  • Designed for use in in vitro binding and cell adhesion assays.
  • Molecular formula C24H27N3O4S; molecular weight 453.55 g·mol⁻¹.
  • High reported purity (≈99.3%).
  • Suitable as a pharmacological probe for assay development and profiling.

Catalog No. 50-002-40093


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