Medchemexpress LLC 2H-1,2-Benzoxaborin-8-carboxylic acid, 3-[[2-[trans-4-[(2-aminoethyl)amino]cyclohexyl]acetyl]amino]-3,4-dihydro-2-hydroxy-, (3R)- | 1613267-49-4 | 98.45% | 389.25 | 1 MG

Supplier:  Medchemexpress LLC HY10912410MG

Taniborbactam (VNRX-5133) is a reversible and selective boronic acid-containing pan-spectrum β-lactamase inhibitor with IC50s ranging from 8-530 nM. It is effective against Gram-negative bacteria and is intended for research use only.

• Reversible and selective boronic acid-containing pan-spectrum β-lactamase inhibitor.
• Effective against Gram-negative bacteria.
• Potent IC50 values against various β-lactamase enzymes, including KPC-2 (30 nM), AmpC (32 nM), OXA-48 (42 nM), and VIM-2 (20 nM).
• Demonstrates high activity in combination with cefepime or meropenem against NDM-1-producing clinical isolates.
• Achieves significant reduction in bacterial counts in in vivo models when combined with cefepime.

Catalog No. 50-003-45269