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Medchemexpress LLC 2H-Furo[2,3-f]oxacyclotridecin-2-one, 4,6,8,10,12,14,16,18,20,22,23,24,25,26-tetradecahydro-3,13,15,17, | 579-13-5 | ≥99.9% | 791.06 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY1658950MG

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Oligomycin A, produced by Streptomyces, functions as a mitochondrial F0F1-ATPase inhibitor with a Ki of 1 μM. It also exhibits anti-fungal properties and is intended for research use only.

  • Targets mitochondrial F0F1-ATPase with a Ki of 1 μM.
  • Shows anti-fungal activity.
  • Exhibits cytotoxicity to NCI-60 cell lines with a GI50 of 10 nM.
  • Inhibits Triton X-100-solubilized ATPase with a Ki of 0.1 μM.
  • Inhibits spermatozoa's ability to achieve feasible in vitro capacitation (IVC) at 2.4 μM.
  • Suppresses progesterone-induced in vitro acrosome exocytosis (IVAE) at 2.4 μM.
  • Displays antiproliferative and antitumor effects against HCT-116 and K562 cells.

Catalog No. 50-003-93824


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