Cayman Chemical 2ImInobIotInhydrobromIde 100mg

Supplier:  Cayman Chemical 38919100 MG

A guanidine-modified biotin derivative and an inhibitor of iNOS and nNOS (Kis = 21.8 and 37.5 µM for the mouse and rat enzymes, respectively); prevents hypoxia-ischemia-induced decreases in brain phosphocreatine and ATP levels and increases in edema in the parietal cortex and striatum, as well as reduces apoptosis in the parietal- and temporal cortex and striatum, in piglets at 0.2 mg/kg every four hours; increases survival of, and decreases electrographic seizures in, hypoxia-ischemia-injured piglets at 0.2 and 1 mg/kg every four hours; LNPs containing 2-iminobiotin conjugated to poly-L-lysine have been used to improve LNP tumor targeting, uptake, and retention compared with LNPs containing biotin conjugated to poly-L-lysine in rats

Catalog No. 50-291-8920