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Cayman Chemical 2Omethyl PAF C18hydrate 100mg

Supplier: Cayman Chemical 60912100 MG

A multi-kinase inhibitor inhibits c-Met Axl Mer FGFR1 FGFR2 and FGFR3 (IC50s 1 7 2 18 17 and 15 nM respectively) inhibits Axl- and c-Met-mediated Akt phosphorylation in MDA-MB-231 cells (IC50s 33 and 50s 50-200 nM) reduces mean tumor volume in GTL-16 and U87MG mouse xenograft models from 6.25-50 mg/kg
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