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Description
- 1-iodo-3,5-dimethylbenzene (5-iodo-m-xylene) is an aryl halide. it can be obtained from 5-bromo-m-xylene, via copper-catalyzed halogen exchange reaction, in the presence of nai or ki in n-buoh or dmf (solvents). it undergoes reaction with phenol in the presence of cufe2o4 nano powder as a recyclable catalyst to afford 1,3-dimethyl-5-phenoxybenzene.1-iodo-3,5-dimethylbenzene (5-iodo-m-xylene) is suitable for use in the synthesis of n-(3,5-xylyl)-n-ethylaniline, an arylamine.it may be used in the following studies:
- α-arylation of ketones
- Copper-catalyzed n-arylation of imidazoles
- Cyanation of 5-iodo-m-xylene to form 3,5-dimethylbenzonitrile
- Synthesis of 1,3-dimethyl-5-phenoxybenzene by nano-cufe2o4 catalyzed c-o cross-coupling with phenol
- Cubr-catalyzed amination of 1-iodo-3,5-dimethylbenzene to form n-allyl-3,5-dimethylbenzenamine
- Copper-catalyzed c-s bond-formation between 5-iodo-m-xylene and thiophenol
- As a starting material in the synthesis of biphenyl-3,3',5,5'-tetracarboxylic acid
- Radical bromination of 5-iodo-m-xylene by n-bromosuccinimide to form 1,3-bis(bromomethyl)-5-iodobenzene
Specifications
Specifications
| CAS | 157837-31-5 |
| Molecular Formula | C9H8N2O |
| Linear Formula | C9H8N2O |
| MDL Number | MFCD00052191 |
| Quantity | 25 mL |
| Molecular Weight (g/mol) | 160.17 |
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