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Medchemexpress LLC 3-[(2-methylphenyl)methylsulfanyl]-6-pyridin-2-ylpyridazine | 894002-50-7 | ≥98.0% | 293.39 g·mol-1 | C17H15N3S | 5 MG
SDP

Supplier:  Medchemexpress LLC HY127415MG

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LDN-212320 is a small-molecule activator of the glutamate transporter GLT-1 (EAAT2) used in research to increase EAAT2 expression and probe glutamate transport-related biology, including pain models. It is supplied as a powder and in solution formats suitable for in vitro and in vivo studies.

  • Activates GLT-1/EAAT2 at the translational level.
  • Small molecule; chemical formula C17H15N3S; molecular weight 293.39 g·mol-1.
  • High purity (≥98.0% by HPLC).
  • Available in mg-scale vials and as a 10 mM solution in DMSO for stock preparation.
  • Soluble in DMSO (50 mg/mL); in vivo formulations achievable at ≥2.5 mg/mL with appropriate co-solvents.
  • Storage: powder -20°C (long term) or 4°C (short term); in solvent -80°C recommended.
  • Used in preclinical studies to modulate glutamate uptake and attenuate nociceptive and chronic pain phenotypes.

Catalog No. 50-002-64345


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