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Medchemexpress LLC 3-[4-(6-(3-(dimethylamino)propoxy)benzo[d]oxazol-2-yl)phenoxy]-N,N-dimethylpropan-1-amine | 1219962-49-8 | 98.8% | 397.519 g·mol⁻¹ | C23H31N3O3 | 25MG
SDP

Supplier:  Medchemexpress LLC HY12460325MG

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AT791 is a small-molecule, orally bioavailable inhibitor of Toll-like receptors TLR7 and TLR9. It blocks DNA-TLR9 interaction in vitro and suppresses cytokine responses such as IL-6 and type I interferon in human and mouse cells, making it suitable for immunology and autoimmune research.

  • Orally bioavailable small-molecule inhibitor of TLR7 and TLR9.
  • Blocks DNA-TLR9 interaction and inhibits TLR-mediated signaling in vitro.
  • Potent activity against TLR9 (low-nanomolar IC50) and weaker activity against TLR7.
  • High-purity solid with good solubility in DMSO (~10 mM) for assay preparation.
  • Appropriate for cellular and in vivo studies of TLR-driven immune responses.

Catalog No. 50-002-36031


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