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Medchemexpress LLC 3,4-Dimethoxycinnamic acid | 2316-26-9 | 208.21 | 1 G
SDP

Supplier:  Medchemexpress LLC HYN17781G

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3,4-Dimethoxycinnamic acid (O-Methylferulic acid) is a monomer extracted and purified from Securidaca inappendiculata Hassk. It exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway.

  • Attenuates the ethanol-induced apoptosis of ethanol-exposed L-02 cells
  • Inhibits the expression levels of Nox4 and p22phox in L-02 cells
  • Attenuates ethanol-induced MAPK phosphorylation in L-02 cells
  • Decreases the expression levels of superoxide dismutase, catalase and phospholipid hydroperoxide gluthione peroxidase
  • Downregulates the levels of Bax/Bcl-2 and the cleaved forms of caspase-3 in a dose- and time-dependent manner

Catalog No. 50-004-15193


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