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Medchemexpress LLC 3-[(4-tert-butylphenyl)methyl]-1-[(3-fluoro-4-methanesulfonamidophenyl)methyl]thiourea | 401907-26-4 | MFCD29770787 | 99.5% | 423.57 g/mol | C20H26FN3O2S2 | 50 MG

Supplier: Medchemexpress LLC HY10066850MG
JYL 1421 is a potent small-molecule antagonist of the transient receptor potential vanilloid 1 (TRPV1) channel, inhibiting capsaicin-evoked Ca2+ accumulation with an IC50 of 8 nM. Supplied for research use in solid form or as a 10 mM solution in DMSO, it is intended for in vitro pharmacology and calcium-flux studies.
- Potent TRPV1 antagonist (IC50 8 nM).
- High purity suitable for research use.
- Available as solid powder or 10 mM solution in DMSO.
- White to off-white powder appearance.
- Stable when stored as powder at -20°C for up to 3 years.
- Validated in capsaicin-evoked calcium accumulation assays.
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