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Medchemexpress LLC 3-[5-[4-(2-hydroxy-2-methyl-1-oxopropyl)-1-piperazinyl]-2-(CF3)phenyl]-4-(indol-3-yl)-pyrrole-2,5-dione | 1260181-14-3 | 99.5% | 526.51 g·mol-1 | C27H25F3N4O4 | 1 MG
SDP

Supplier:  Medchemexpress LLC HY1082641MG

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TCS 21311 is a small-molecule inhibitor of Janus kinase 3 (JAK3) used as a biochemical and pharmacological tool. It exhibits potent enzymatic activity (IC50 ≈ 8 nM) and strong selectivity for JAK3 over JAK1, JAK2, and TYK2, making it suitable for studies of JAK3-mediated signaling.

  • Potent JAK3 inhibition with an IC50 of approximately 8 nM.
  • Greater than 100-fold selectivity versus JAK1, JAK2, and TYK2.
  • Well-defined molecular properties: C27H25F3N4O4, molecular weight 526.51 g·mol-1.
  • High purity suitable for research use (~99.5% by HPLC).
  • Supplied in small-quantity packaging ideal for screening and biochemical assays.

Catalog No. 50-002-42569


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