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Medchemexpress LLC 3-[5-[(5-chloropyridin-2-yl)methyl]-1,3,4-oxadiazol-2-yl]-5-(2,6-dimethoxyphenyl)-6-(ethoxymethyl)-4-hydroxy... | 2055200-88-7 | 99.4% | C24H23ClN4O6 | 10MG
SDP

Supplier:  Medchemexpress LLC HY13948510MG

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A selective, orally active small-molecule agonist of the apelin (APJ) receptor for preclinical cardiac research. It exhibits subnanomolar potency at human APJ and engages multiple downstream signaling pathways; efficacy has been shown in animal models with increased stroke volume and cardiac output.

  • High potency at human APJ (EC50 ≈ 0.02 nM).
  • Selective apelin (APJ) receptor agonist.
  • Orally active small molecule suitable for in vivo studies.
  • Activates β-arrestin recruitment and ERK phosphorylation.
  • Demonstrated to increase stroke volume and cardiac output in animal models.
  • Supplied as a solid, off-white to light yellow material.
  • High purity (≈99.4%).

Catalog No. 50-002-61843


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