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Medchemexpress LLC 3-[5-[(5-chloropyridin-2-yl)methyl]-1,3,4-oxadiazol-2-yl]-5-(2,6-dimethoxyphenyl)-6-(ethoxymethyl)-4-hydroxy... | 2055200-88-7 | 99.4% | C24H23ClN4O6 | 10MG

Supplier: Medchemexpress LLC HY13948510MG
A selective, orally active small-molecule agonist of the apelin (APJ) receptor for preclinical cardiac research. It exhibits subnanomolar potency at human APJ and engages multiple downstream signaling pathways; efficacy has been shown in animal models with increased stroke volume and cardiac output.
- High potency at human APJ (EC50 ≈ 0.02 nM).
- Selective apelin (APJ) receptor agonist.
- Orally active small molecule suitable for in vivo studies.
- Activates β-arrestin recruitment and ERK phosphorylation.
- Demonstrated to increase stroke volume and cardiac output in animal models.
- Supplied as a solid, off-white to light yellow material.
- High purity (≈99.4%).
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