Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000299221

Medchemexpress LLC 3-[[[5-(6-Methyl-2-pyridinyl)-4-triazolo[1,5-a]pyridin-6-yl-1H-imidazol-2-yl]methyl]amino]benzonitrile | 1352609-28-9 | 98.8% | 406.44 | C23H18N8 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY1876610MG

Encompass_Preferred

EW-7195 is a potent, selective ALK5 (TGFβR1) inhibitor for research use that blocks TGF-β1-induced Smad signaling, epithelial-to-mesenchymal transition, and metastatic progression in preclinical studies. It provides low-nanomolar potency and is supplied with high purity for laboratory assays.

  • Potent ALK5 inhibition with low-nanomolar IC50.
  • High selectivity over related kinases, >300-fold versus p38α.
  • Blocks TGF-β1-induced Smad signaling and epithelial-to-mesenchymal transition.
  • Demonstrated anti-metastasis activity in preclinical models.
  • High purity suitable for research applications.
  • Soluble in DMSO for assay preparation.

Catalog No. 50-002-99221


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.