3',5,7-Trihydroxy-4'-methoxyflavanone, 97%

Description

CAS: 520-33-2 | C16H14O6 | 302.28 g/mol

(±)-Hesperetin is an antioxidant flavonoid. Induces G1-phase cell cycle arrest. Anti-inflammatory. (±)-Hesperetin suppresses NF-κB activation. Reduces cholesterol biosynthesis. Inhibits lipid peroxidation. Neuroprotective against neuronal oxidative damage.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
(±)-Hesperetin is an antioxidant flavonoid. Induces G1-phase cell cycle arrest. Anti-inflammatory. (±)-Hesperetin suppresses NF-κB activation. Reduces cholesterol biosynthesis. Inhibits lipid peroxidation. Neuroprotective against neuronal oxidative damage.

Solubility
Soluble in water (partly), dilute alkalis, and ethanol (50 mg/ml).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Stable under recommended storage conditions. Keep away from strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 520-33-2
• Molecular Formula: C16H14O6
• Molecular Weight (g/mol): 302.28
• MDL Number: MFCD00075646
• InChI Key: AIONOLUJZLIMTK-AWEZNQCLSA-N
• Synonym: hesperetin, hesperitin, 3',5,7-trihydroxy-4'-methoxyflavanone, hesperin, yso2, cyanidanon 4'-methyl ether 1626, 5,7,3'-trihydroxy-4'-methoxyflavanone, --hesperetin, prestwick_908, unii-q9q3d557f1
• PubChem CID: 72281
• ChEBI: CHEBI:28230
• IUPAC Name: (2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydrochromen-4-one
• SMILES: COC1=CC=C(C=C1O)[C@@H]1CC(=O)C2=C(O)C=C(O)C=C2O1

• Melting Point: 227°C to 232°C
• Quantity: 25 g
• Beilstein: 309850
• Merck Index: 14,4670
• Solubility Information: Soluble in water (partly),dilute alkalis,and ethanol (50mg/ml).
• Formula Weight: 302.3
• Percent Purity: 97%
• Chemical Name or Material: 3',5,7-Trihydroxy-4'-methoxyflavanone

Safety and Handling

Hazard Category	Warning
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	GHS P Statement P261-P280-P305+P351+P338-P304+P340-P405-P501a Avoid breathing dust/fume/gas/mist/vapors/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.
EINECSNumber	208-290-2
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only