3,5-Bis(trifluoromethyl)aniline, 98%

Description

CAS: 328-74-5 | C8H5F6N | 229.125 g/mol

3,5-Bis(trifluoromethyl)aniline was used in the synthesis of N-[2-hydroxy-1-naphthylidene]-3, 5-bis(trifluoromethyl)aniline, Schiff?s base and 5,7-bis(trifluoromethyl)aniline. It was also used in the synthesis of N-1-phenylethyl-3,5-bis(trifluoromethyl)aniline via titanium-catalyzed hydroamination reaction and N,N?-bis[3,5-bis(tri-fluoromethyl)phenyl]thiourea, organocatalyst.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3,5-Bis(trifluoromethyl)aniline was used in the synthesis of N-[2-hydroxy-1-naphthylidene]-3, 5-bis(trifluoromethyl)aniline, Schiff′s base and 5,7-bis(trifluoromethyl)aniline. It was also used in the synthesis of N-1-phenylethyl-3,5-bis(trifluoromethyl)aniline via titanium-catalyzed hydroamination reaction and N,N′-bis[3,5-bis(tri-fluoromethyl)phenyl]thiourea, organocatalyst.

Solubility
Not miscible in water.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 328-74-5
• Molecular Formula: C8H5F6N
• Molecular Weight (g/mol): 229.125
• MDL Number: MFCD00000394
• InChI Key: CDIDGWDGQGVCIB-UHFFFAOYSA-N
• Synonym: 3,5-bis trifluoromethyl aniline, 3,5-di trifluoromethyl aniline, benzenamine, 3,5-bis trifluoromethyl, 3,5-bis trifluoromethyl benzenamine, 3',5'-bis-trifluoromethyl aniline, 3,5-bis-trifluoromethylaniline, alpha,alpha,alpha,alpha',alpha',alpha'-hexafluoro-3,5-xylidine, 3,5-bis-trifluoromethyl-phenylamine, aniline, 3,5-bis trifluoromethyl
• PubChem CID: 9480
• IUPAC Name: 3,5-bis(trifluoromethyl)aniline
• SMILES: C1=C(C=C(C=C1C(F)(F)F)N)C(F)(F)F

• Density: 1.473
• Boiling Point: 75°C to 78°C (10 mmHg)
• Flash Point: 83°C (181°F)
• Odor: Recognizable
• Refractive Index: 1.434
• Quantity: 10 g
• UN Number: UN2810
• Beilstein: 654318
• Solubility Information: Not miscible in water.
• Formula Weight: 229.13
• Percent Purity: 98%
• Chemical Name or Material: 3,5-Bis(trifluoromethyl)aniline

Safety and Handling

Hazard Category	H227-H302+H312+H332-H315-H319-H335-H373
Hazard Statement	GHS H Statement H331-H373-H227-H302-H312-H315-H319 Toxic if inhaled. May cause damage to organs through prolonged or repeated exposure. Combustible liquid. Harmful if swallowed. Harmful in contact with skin. Causes skin irritation. Causes serious eye irritation.
Precautionary Statement	P210-P235-P260-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P314-P330-P332+P313-P362-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC, LIQUIDS, ORGANIC, N.O.S.
EINECSNumber	206-335-0
RTECSNumber	ZE9800000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only