3,5-Di-tert-butyl-2-hydroxybenzaldehyde, 99%

Description

CAS: 37942-07-7 | C15H22O2 | 234.339 g/mol

3,5-Di-tert-butyl-2-hydroxybenzaldehyde is used in the synthesis of Mn(III)-salen complex and its diamino precursor 5,6-diamino-5,6-dideoxy-1,2-O-isopropylidene-3-O-methyl-β-L-idofuranose, chiral Schiff base ligand for an enantioselective copper-catalyzed addition of phenyl acetylene to imines, chiral oxazolidine ligand for the enantioselective addition of diethyl zinc to aldehydes and tin Schiff base complexes with histidine analogues. It has antibacterial activity and is used in the preparation nickel complexes. It is structurally related to 3,5-di-t-butylcatechol (DTCAT) but is not as potent an activator of rat skeletal muscle ryanodine receptor Ca2+ channel (RyRC).

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3,5-Di-tert-butyl-2-hydroxybenzaldehyde is used in the synthesis of Mn(III)-salen complex and its diamino precursor 5,6-diamino-5,6-dideoxy-1,2-O-isopropylidene-3-O-methyl-β-L-idofuranose, chiral Schiff base ligand for an enantioselective copper-catalyzed addition of phenyl acetylene to imines, chiral oxazolidine ligand for the enantioselective addition of diethyl zinc to aldehydes and tin Schiff base complexes with histidine analogues. It has antibacterial activity and is used in the preparation nickel complexes. It is structurally related to 3,5-di-t-butylcatechol (DTCAT) but is not as potent an activator of rat skeletal muscle ryanodine receptor Ca2+ channel (RyRC).

Solubility
Soluble in DMSO and methanol.

Notes
Air sensitive. Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Specifications

Chemical Identifiers

• CAS: 37942-07-7
• Molecular Formula: C15H22O2
• Molecular Weight (g/mol): 234.339
• MDL Number: MFCD00191998
• InChI Key: RRIQVLZDOZPJTH-UHFFFAOYSA-N
• Synonym: 3,5-di-tert-butyl-2-hydroxybenzaldehyde, 3,5-di-tert-butylsalicylaldehyde, 3,5-bis 1,1-dimethylethyl-2-hydroxy-benzaldehyde, benzaldehyde, 3,5-bis 1,1-dimethylethyl-2-hydroxy, 3,5-di-t-butylsalicylaldehyde, 3,5-di-tert-butyl-2-hydroxy-benzaldehyde, benzaldehyde, 2-hydroxy, 3,5-di t-butyl, 3,5-bis tert-butyl-2-hydroxybenzaldehyde, pubchem11247, acmc-1aete
• PubChem CID: 688023
• IUPAC Name: 3,5-ditert-butyl-2-hydroxybenzaldehyde
• SMILES: CC(C)(C)C1=CC(=C(C(=C1)C=O)O)C(C)(C)C

• Melting Point: 59°C to 61°C
• Assay Percent Range: 0.99
• Quantity: 5 g
• Beilstein: 1877810
• Sensitivity: Air Sensitive
• Solubility Information: Soluble in DMSO and methanol.
• Formula Weight: 234.34
• Percent Purity: 99%
• Chemical Name or Material: 3,5-Di-tert-butyl-2-hydroxybenzaldehyde

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	000-000-0
TSCA	No
storageNote1	Air Sensitive
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only