Medchemexpress LLC 3-(6-chloropyridine-3-yloxymethyl)-2-azabicyclo[3.1.0]hexane hydrochloride | 2414674-71-6 | 99.4% | C11H14Cl2N2O | 10MG

Supplier:  Medchemexpress LLC HY13614610MG

This small-molecule hydrochloride is a potent, selective, brain-penetrant, and orally bioavailable neuronal nicotinic acetylcholine α4β2 receptor antagonist with a reported Ki ≈ 1.5 nM and demonstrated antidepressant activity in preclinical models. It is described in the literature and supplier listings as a crystalline, non-hygroscopic salt with favorable ADME and safety properties.

• Potent, selective α4β2 receptor antagonism (Ki ≈ 1.5 nM).
• Oral bioavailability and brain penetration demonstrated in preclinical studies.
• Favorable ADME profile with low drug-drug interaction liability.
• Crystalline hydrochloride salt with stable physicochemical properties.
• Reported high purity in supplier analyses (example: 99.4%).
• Supported by published preclinical studies and supplier data.

Catalog No. 50-002-60185