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3-Amino-2-hydroxypyridine, 98%

Catalog No. AAH6448006
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Quantity:
1 g
5 g

CAS: 33630-99-8 | C5H6N2O | 110.12 g/mol

It is used as pharmaceutical intermediate. It is involved in synthesis of functionalized pyrido[4,3-b][1,4]oxazine and imidazo[1,2-a]pyridine derivatives. The use of ethyl 2-chloro-3-oxopropanoate with 2-amino-3-hydroxypyridine or 3-amino-4-hydroxypyridine led, respectively, to imidazo[1,2-a]pyridine derivatives or ethyl pyrido[4,3-b][1,4] oxazine-2-carboxylate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is used as pharmaceutical intermediate. It is involved in synthesis of functionalized pyrido[4,3-b][1,4]oxazine and imidazo[1,2-a]pyridine derivatives. The use of ethyl 2-chloro-3-oxopropanoate with 2-amino-3-hydroxypyridine or 3-amino-4-hydroxypyridine led, respectively, to imidazo[1,2-a]pyridine derivatives or ethyl pyrido[4,3-b][1,4] oxazine-2-carboxylate.

Solubility
Slightly soluble in water.

Notes
Store in cool dry place. Keep container tightly closed. Incompatible with oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 33630-99-8
Molecular Formula C5H6N2O
Molecular Weight (g/mol) 110.12
MDL Number MFCD03411556
InChI Key VTSFNCCQCOEPKF-UHFFFAOYSA-N
Synonym 3-amino-2-hydroxypyridine, 3-aminopyridin-2-ol, 3-amino-2-pyridinol, 3-aminopyridin-2 1h-one, 2 1h-pyridinone, 3-amino, 3-amino-2-pyridone, 3-amino-pyridin-2-ol, 2-pyridinol, 3-amino, 2-hydroxy-3-aminopyridine, 3-aminohydropyridin-2-one
PubChem CID 322353
SMILES NC1=CC=CNC1=O

Specifications

Color Brown
Quantity 5 g
Beilstein 109849
Solubility Information Slightly soluble in water.
IUPAC Name 3-amino-1H-pyridin-2-one
Formula Weight 110.12
Percent Purity 98%
Physical Form Crystalline Solid
Chemical Name or Material 3-Amino-2-hydroxypyridine
Hazard Category H315-H319-H335
Hazard Statement GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA No
storageNote1 2° to 8°C
Recommended Storage Keep cold; Store under Nitrogen

RUO – Research Use Only

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