3-Amino-2-hydroxypyridine, 98%

Description

CAS: 33630-99-8 | C5H6N2O | 110.12 g/mol

It is used as pharmaceutical intermediate. It is involved in synthesis of functionalized pyrido[4,3-b][1,4]oxazine and imidazo[1,2-a]pyridine derivatives. The use of ethyl 2-chloro-3-oxopropanoate with 2-amino-3-hydroxypyridine or 3-amino-4-hydroxypyridine led, respectively, to imidazo[1,2-a]pyridine derivatives or ethyl pyrido[4,3-b][1,4] oxazine-2-carboxylate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is used as pharmaceutical intermediate. It is involved in synthesis of functionalized pyrido[4,3-b][1,4]oxazine and imidazo[1,2-a]pyridine derivatives. The use of ethyl 2-chloro-3-oxopropanoate with 2-amino-3-hydroxypyridine or 3-amino-4-hydroxypyridine led, respectively, to imidazo[1,2-a]pyridine derivatives or ethyl pyrido[4,3-b][1,4] oxazine-2-carboxylate.

Solubility
Slightly soluble in water.

Notes
Store in cool dry place. Keep container tightly closed. Incompatible with oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 33630-99-8
• Molecular Formula: C5H6N2O
• Molecular Weight (g/mol): 110.12
• MDL Number: MFCD03411556
• InChI Key: VTSFNCCQCOEPKF-UHFFFAOYSA-N
• Synonym: 3-amino-2-hydroxypyridine, 3-aminopyridin-2-ol, 3-amino-2-pyridinol, 3-aminopyridin-2 1h-one, 2 1h-pyridinone, 3-amino, 3-amino-2-pyridone, 3-amino-pyridin-2-ol, 2-pyridinol, 3-amino, 2-hydroxy-3-aminopyridine, 3-aminohydropyridin-2-one
• PubChem CID: 322353
• SMILES: NC1=CC=CNC1=O

• Color: Brown
• Quantity: 5 g
• Beilstein: 109849
• Solubility Information: Slightly soluble in water.
• IUPAC Name: 3-amino-1H-pyridin-2-one
• Formula Weight: 110.12
• Percent Purity: 98%
• Physical Form: Crystalline Solid
• Chemical Name or Material: 3-Amino-2-hydroxypyridine

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA	No
storageNote1	2° to 8°C
Recommended Storage	Keep cold; Store under Nitrogen

SDS

RUO – Research Use Only