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Medchemexpress LLC 3α-Aminocholestane | 2206-20-4 | 98.0% | 387.68 | 25 MG
Supplier: Medchemexpress LLC 25MGHY19776
3α-Aminocholestane is a selective SH2 domain-containing inositol-5′-phosphatase 1 (SHIP1) inhibitor with an IC50 of ~2.5 μM. It is for research use only and not sold to patients.
- Appears as a white to off-white solid
- Stored at -20°C for 3 years or 4°C for 2 years as powder
- Stored at -80°C for 2 years or -20°C for 1 year in solvent
- Soluble in ethanol (50 mg/mL), slightly soluble in DMSO
- Exhibits antiviral activity against Influenza A/PR8/34 (H1N1) virus in MDCK-II cells
- Reduces OPM2 cell viability
- Blocks cell cycle progression in G0/G1 phase in RPMI8226 and U266 cells
- Reduces multiple myeloma (MM) growth in vivo and enhances survival of mice
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