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Medchemexpress LLC 3α-Aminocholestane | 2206-20-4 | 98.0% | 387.68 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY197765MG

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3α-Aminocholestane is a selective inhibitor of SH2 domain-containing inositol-5′-phosphatase 1 (SHIP1) with an IC50 of approximately 2.5 μM. It is intended for research use only. This compound effectively reduces multiple myeloma growth in vivo and blocks cell cycle progression.

  • Selectively inhibits SHIP1.
  • Effectively reduces OPM2 cell viability.
  • Blocks cell cycle progression in G0/G1 phase or reduces cells in S phase.
  • Reduces multiple myeloma (MM) growth in vivo.
  • Significantly enhances survival of mice after tumor challenge.

Catalog No. 50-004-02004


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