3-Bromo-1-trimethylsilyl-1-propyne, 98%

Description

CAS: 38002-45-8 | C6H11BrSi | 191.143 g/mol

3-Bromo-1-trimethylsilyl-1-propyne is used in the preparation of tetrahydroisoquinoline-3-carboxylic acid derivatives. It acts as a propargylating agent and used for the alkylation of dianion of beta-keto esters at gamma-carbon. It plays an important role in the synthesis of allenic alcohols and terminal conjugated enynes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3-Bromo-1-trimethylsilyl-1-propyne is used in the preparation of tetrahydroisoquinoline-3-carboxylic acid derivatives. It acts as a propargylating agent and used for the alkylation of dianion of beta-keto esters at gamma-carbon. It plays an important role in the synthesis of allenic alcohols and terminal conjugated enynes.

Solubility
Immiscible with water.

Notes
Store in cool place. Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 38002-45-8
• Molecular Formula: C6H11BrSi
• Molecular Weight (g/mol): 191.143
• MDL Number: MFCD00134460
• InChI Key: GAPRPFRDVCCCHR-UHFFFAOYSA-N
• Synonym: 3-bromo-1-trimethylsilyl-1-propyne, 3-bromoprop-1-yn-1-yl trimethylsilane, 3-bromo-1-propynyl trimethylsilane, 3-trimethylsilyl propargyl bromide, 3-bromoprop-1-ynyl trimethyl silane, silane, 3-bromo-1-propynyl trimethyl, 3-bromoprop-1-yn-1-yl trimethyl silane, acmc-1cthe, ksc496i3r
• PubChem CID: 642589
• IUPAC Name: 3-bromoprop-1-ynyl(trimethyl)silane
• SMILES: C[Si](C)(C)C#CCBr

• Boiling Point: 44°C to 45°C (2mmHg)
• Quantity: 5 g
• Linear Formula: BrCH₂C≡CSi(CH₃)₃
• Beilstein: 2037650
• Flash Point: 63°C (145°F)
• Solubility Information: Immiscible with water.
• Formula Weight: 191.14
• Percent Purity: 98%
• Refractive Index: 1.483
• Density: 1.17
• Chemical Name or Material: 3-Bromo-1-trimethylsilyl-1-propyne

Safety and Handling

Hazard Category	H227-H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335-H227 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Combustible liquid.
Precautionary Statement	P210-P235-P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P370+P378q-P501c
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only