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Sigma Aldrich 3-Bromo-5-((Trimethylsilyl)Ethynyl)Benzenesulfonyl Fluoride

Catalog No. 90085950MG Shop All MilliporeSigma Sigma Organic Chemistry Products
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90-085-950MG 100 mg
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MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

3-Bromo-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.Technology Spotlight: Trifunctional Probe Building BlocksChemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

Specifications

CAS 218460-00-5
Melting Point 152.2°C to 156.3°C
Molecular Formula C22H40BF4P2Rh
Linear Formula C22H40BF4P2Rh
Quantity 100 mg
Molecular Weight (g/mol) 556.21 g/mol
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