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Medchemexpress LLC 3-Bromopyruvic acid | 1113-59-3 | MFCD00002587 | >98.0% | 166.96 | 1 G
Supplier: Medchemexpress LLC HY199921G
3-Bromopyruvate (Bromopyruvic acid) is a synthetic analogue of pyruvate and a potent inhibitor of hexokinase II (HK-II), an enzyme frequently overexpressed in cancer cells, contributing to their high glycolytic rates. Its high tumor selectivity allows it to interfere with glycolysis, a primary energy pathway in many cancer cells, thereby inhibiting cell growth and inducing apoptosis. In breast cancer cells, 3-Bromopyruvate has been shown to induce autophagy by stimulating the formation of reactive oxygen species (ROS). Additionally, this compound exhibits significant antimicrobial activities.
- Potent hexokinase II inhibitor.
- Exhibits high tumor selectivity.
- Inhibits cell growth and induces apoptosis.
- Stimulates reactive oxygen species formation.
- Demonstrates antimicrobial activities.
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