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3-Butyn-2-one, 98%
Description
3-Butyn-2-one was used in the synthesis of clerodane diterpenoid (±)-sacacarin. It was used as substrate in stereoselective, conjugate arylation mediated by gallium(III) chloride leading to (E)-α,β-unsaturated ketones. 3-Butyn-2-one undergoes asymmetric double-Michael reaction with ortho-tosylamidophenyl malonate catalyzed by chiral aminophosphines to yield indolines2. It undergoes double Michael reaction with nitrogen-containing tethered diacid to give pipecolic acid derivatives. 3-Butyn-2-one, is used as a reactant with Dimethyl acetone-1,3-dicarboxylate, under mild conditions to give a benzenoid product via a Michael addition - aldol cyclization process.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
3-Butyn-2-one was used in the synthesis of clerodane diterpenoid (+/-)-sacacarin. It was used as substrate in stereoselective, conjugate arylation mediated by gallium(III) chloride leading to (E)-α,β-unsaturated ketones. 3-Butyn-2-one undergoes asymmetric double-Michael reaction with ortho-tosylamidophenyl malonate catalyzed by chiral aminophosphines to yield indolines2. It undergoes double Michael reaction with nitrogen-containing tethered diacid to give pipecolic acid derivatives. 3-Butyn-2-one, is used as a reactant with Dimethyl acetone-1,3-dicarboxylate, under mild conditions to give a benzenoid product via a Michael addition - aldol cyclization process.
Solubility
It is soluble in water.
Notes
Stable under normal temperatures and pressures. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from oxidizing agents.
Specifications
Specifications
| Density | 0.87 |
| Boiling Point | 84°C to 86°C |
| Flash Point | −1°C (30°F) |
| Refractive Index | 1.406 |
| Quantity | 1 g |
| UN Number | UN1992 |
| Beilstein | 605353 |
| Solubility Information | It is soluble in water. |
| Formula Weight | 68.08 |
| Percent Purity | 98% |
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Safety and Handling
| Hazard Category | H225-H300-H315-H319-H335 |
| Hazard Statement | GHS H Statement H225-H300-H318-H315-H335 Highly flammable liquid and vapor. Fatal if swallowed. Causes serious eye damage. Causes skin irritation. May cause respiratory irritation. |
| Precautionary Statement | P210-P233-P235-P240-P241-P242-P243-P261-P264b-P270-P271-P280-P301+P310-P303+P361+P353-P304+P340-P305+P351+P338-P312-P330-P332+P313-P363-P370+P378q-P501c |
| DOTInformation | Transport Hazard Class: 3; Packing Group: II; Proper Shipping Name: FLAMMABLE LIQUIDS, TOXIC, N.O.S. |
| EINECSNumber | 215-834-2 |
| TSCA | No |
| Recommended Storage | Keep cold |
RUO – Research Use Only
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