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Medchemexpress LLC 3-Chloro-N-(4-hydroxy-2-oxo-2H-chromen-3-yl)benzamide | 94205-22-8 | C16H10ClNO4 | 25 MG
Supplier: Medchemexpress LLC 25MGHY152084
Anticancer agent 93 is a 4-Hydroxycoumarin derivative. It can inhibit invasion and migration of lung cancer cells by modulating the expression of epithelial-mesenchymal transition (EMT) effectors.
- 4-Hydroxycoumarin derivative
- Inhibits invasion and migration of lung cancer cells
- Modulates expression of epithelial-mesenchymal transition (EMT) effectors
- Purity of 98.01%
- White to off-white solid appearance
- Inhibits A549 cell invasion by approximately 50% at concentrations of 5-15 μM for 24 hours
- Significantly inhibits A549 cell migration at 15 μM for 24-72 hours
- Inhibits lung cancer cell motility by downregulating EMT markers at 5-15 μM for 4 hours
- Decreases expression of N-cadherin and E-cadherin in A549 cells
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