3-Chlorobenzeneboronic acid, 97%

Description

CAS: 63503-60-6 | C6H6BClO2 | 156.37 g/mol

It is employed as a reactant involved in 1,4-conjugate addition reactions with ethenesulfonamides to form arylethanesulfonamides, Suzuki-Miyaura reactions with dibromotrifluoromethylbenzene, cross-coupling reactions with diazoesters3 or potassium cyanate. It is involved in the synthesis of biarylketones and phthalides and synthesis of inhibitors including PDE4 inhibitors6 among others.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is employed as a reactant involved in 1,4-conjugate addition reactions with ethenesulfonamides to form arylethanesulfonamides, Suzuki-Miyaura reactions with dibromotrifluoromethylbenzene, cross-coupling reactions with diazoesters3 or potassium cyanate. It is involved in the synthesis of biarylketones and phthalides and synthesis of inhibitors including PDE4 inhibitors6 among others.

Solubility
Slightly soluble in water. soluble in ether, tetrahydrofuran,, dimethyl sulfoxide, dimethyl formamide, methanol.

Notes
Store at room temperature. Incompatible with oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 63503-60-6
• Molecular Formula: C6H6BClO2
• Molecular Weight (g/mol): 156.37
• MDL Number: MFCD00161354
• InChI Key: SDEAGACSNFSZCU-UHFFFAOYSA-N
• Synonym: 3-chlorophenyl boronic acid, 3-chlorobenzeneboronic acid, 3-chlorophenyl boranediol, 3-chlorophenylbornic acid, 3-chloro benzene boronic acid, m-chlorophenylboronic acid, 3-chloro-phenyl-boronic acid, boronic acid, 3-chlorophenyl, pubchem1785
• PubChem CID: 2734323
• IUPAC Name: (3-chlorophenyl)boronic acid
• SMILES: OB(O)C1=CC(Cl)=CC=C1

• Melting Point: 180°C to 185°C
• Quantity: 25 g
• Beilstein: 2936343
• Solubility Information: Slightly soluble in water. soluble in ether,tetrahydrofuran,,dimethyl sulfoxide,dimethyl formamide,methanol.
• Formula Weight: 156.38
• Percent Purity: 97%
• Chemical Name or Material: 3-Chlorobenzeneboronic acid

Safety and Handling

Hazard Category	H302-H312-H315-H319-H332-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
EINECSNumber	000-000-0
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only