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Medchemexpress LLC [3-Cyano-5-[[[2,4-dimethyl-5-[6-(3-pyridinyl)-1H-imidazo[1,2-b]pyrazol-1-yl]phenyl]amino]carb | 1448316-08-2 | >98.0% | 558.53 | C26H19F5N6OS | 50 MG
SDP

Supplier:  Medchemexpress LLC HY10075650MG

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BAY-826 is a small-molecule chemical probe that selectively inhibits the receptor tyrosine kinase TIE-2 (TEK). It shows low-nanomolar biochemical potency and potent cellular activity, and is supplied for research use in solid and DMSO solution formats for preclinical mechanism-of-action and signaling studies.

  • Selective TIE-2 inhibition (Kd = 1.6 nM).
  • Potent cellular activity (EC50 = 1.3 nM for TIE-2 autophosphorylation in HUVECs).
  • Characterized kinase selectivity with limited off-target binding.
  • Available as solid (5-500 mg) and as 10 mM solution in DMSO.
  • Suitable for preclinical research applications and mechanistic studies.

Catalog No. 50-002-13553


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