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Medchemexpress LLC 3-(cyclopropylmethyl)-7-((4-phenylpiperidin-1-yl)methyl)-8-(trifluoromethyl)-triazolopyridine | 1254980-38-5 | 98.8% | 5 MG
SDP

Catalog No. 5000234392
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JNJ-46281222 is an mGlu2-selective positive allosteric modulator used as a research tool in receptor binding and functional assays; it has nanomolar affinity and is supplied as a high-purity solid or DMSO solution for in vitro studies.

  • Metabotropic glutamate receptor 2 (mGlu2)-selective positive allosteric modulator
  • High affinity: Kd = 1.7 nM
  • Functional potency: pEC50 = 7.71 (EC50 ≈ 19-21 nM in CHO assays)
  • Molecular formula C23H25F3N4; molecular weight 414.47 g·mol-1
  • High purity (98.77%)
  • Available as solid powder and as 10 mM solution in DMSO
  • Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months)
  • For research use only; not for human or clinical use

Catalog No. 50-002-34392 Supplier Medchemexpress LLC Supplier No. HY1205305MG
May include imposed supplier surcharges.
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JNJ-46281222 is an mGlu2-selective positive allosteric modulator used as a research tool in receptor binding and functional assays; it has nanomolar affinity and is supplied as a high-purity solid or DMSO solution for in vitro studies.

  • Metabotropic glutamate receptor 2 (mGlu2)-selective positive allosteric modulator
  • High affinity: Kd = 1.7 nM
  • Functional potency: pEC50 = 7.71 (EC50 ≈ 19-21 nM in CHO assays)
  • Molecular formula C23H25F3N4; molecular weight 414.47 g·mol-1
  • High purity (98.77%)
  • Available as solid powder and as 10 mM solution in DMSO
  • Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months)
  • For research use only; not for human or clinical use

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