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Cayman Chemical 3-Cyno-7-ethoxycoumarIn 50mg
Supplier: Cayman Chemical 2544150 MG
A PAI-1 inhibitor (IC50 6.95 UM) inhibits formation of a complex consisting of tPA PAI-1 and GFP on VECsin vitro prolonging the time that tPA is retained on VECs decreases blood clot weight in a rat model of arteriovenous shunt thrombosis when used at doses of 10 and 50 mg/kg increases the time to primary occlusion in a ferric chloride-treated carotid artery thrombosis model in rats when used at doses of 1 and 3 mg/kg increases the time to primary occlusion in a cynomolgus monkey model of photochemical-induced arterial thrombosis when used at a dose of 10 mg/kg does not affect platelet activity activated partial thromboplastin time prothrombin time or prolong bleeding time
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