Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Cayman Chemical 3-Deaza-2-deoxyadenosIn 5mg
Supplier: Cayman Chemical 90007865 MG
A SERD selectively induces degradation of ERa in MCF-7 cancer cells (EC50 0.2 nM) over ERB glucocorticoid androgen progesterone and mineralocorticoid receptors at 5 UM but does activate ERB signaling in reporter cells decreases 17B-estradiol-induced proliferation of MCF-7 cells expressing wild-type ERa MCF-7 cells expressing ERaY537S and MCF-7 cells expressing ERaD538G (EC50s 20 331 and 595 nM respectively) reduces tumor volume in a PDX mouse model of tamoxifen-resistant breast cancer
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction