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Medchemexpress LLC 3-Deazaadenosine | 6736-58-9 | ≥99.0% | 266.26 | 10 MG
SDP

Supplier:  Medchemexpress LLC HYW01333210MG

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3-Deazaadenosine is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 μM. It exhibits anti-inflammatory, anti-proliferative, and anti-HIV activity.

  • Inhibits S-adenosylhomocysteine hydrolase
  • Ki of 3.9 μM
  • Anti-inflammatory activity
  • Anti-proliferative activity
  • Anti-HIV activity
  • Inhibits p24 antigen in PBMCs infected with HIV-1 isolates
  • Inhibits LPS-induced TNF-α mRNA expression
  • Enhances nuclear translocation of NF-κB but blocks LPS-induced NF-κB transcriptional activity
  • Inhibits phosphorylation of Raf, ERK, protein-dependent kinase 1, protein kinase B (Akt), and forkhead transcription factor FoxO1a
  • Suppresses vascular smooth muscle cell (VSMC) proliferation via interfering with Ras signaling

Catalog No. 50-004-54292


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