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Medchemexpress LLC 3-epi-Vitamin D3 | 57651-82-8 | C27H44O | 5 MG
Supplier: Medchemexpress LLC HY15398C5MG
A Vitamin D3 analogue, this compound acts as a Hedgehog pathway inhibitor with an IC50 of 39.2 μM in U87MG cells. It significantly upregulates Cyp24A1 in U87MG, HT-29, and C3H10T1/2 cells at concentrations of 5 or 10 μM. It exhibits antiproliferative activity against human U87MG cells after 72 hours, as measured by MTS assay.
- Exhibits specific inhibitory activity against the Hedgehog pathway.
- Demonstrates antiproliferative effects in certain human cell lines.
- Induces upregulation of a key metabolic enzyme in multiple cell types.
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