Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

3-Hydroxy-4-methoxybenzaldehyde, 98%

Catalog No. AAA1286606
Click to view available options
Quantity:
5 g
25 g
100 g

CAS: 621-59-0 | C8H8O3 | 152.149 g/mol

3-Hydroxy-4-methoxybenzaldehyde acts as a precursor for the stereoselective synthesis of the anticancer drug (Z)-combretastatin A-4 and glycitein. It also used as an important raw material for the preparation of morphine. Further, it is involved in the preparation of Schiff- bases by reacting with furan-2-carboxylic acid hydrazide and thiophene-2-carboxylic acid hydrazide. In addition to this, it is used to prepare (Z)-2-(3-hydroxy-4-methoxybenzylidene)-1-azabicyclo[2.2.2]octan-3-one by reacting with with1-azabicyclo[2.2.2]octan-3-one.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3-Hydroxy-4-methoxybenzaldehyde acts as a precursor for the stereoselective synthesis of the anticancer drug (Z)-combretastatin A-4 and glycitein. It also used as an important raw material for the preparation of morphine. Further, it is involved in the preparation of Schiff- bases by reacting with furan-2-carboxylic acid hydrazide and thiophene-2-carboxylic acid hydrazide. In addition to this, it is used to prepare (Z)-2-(3-hydroxy-4-methoxybenzylidene)-1-azabicyclo[2.2.2]octan-3-one by reacting with with1-azabicyclo[2.2.2]octan-3-one.

Solubility
Soluble in acetone and methanol.

Notes
Air sensitive. Store in a cool place. Incompatible with strong oxidizing agents and strong bases.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 621-59-0
Molecular Formula C8H8O3
Molecular Weight (g/mol) 152.149
MDL Number MFCD00003369
InChI Key JVTZFYYHCGSXJV-UHFFFAOYSA-N
Synonym isovanillin, isovanilline, 3-hydroxy-p-anisaldehyde, 5-formylguaiacol, benzaldehyde, 3-hydroxy-4-methoxy, iso-vanillin, 3-hydroxyanisaldehyde, isovanilin, isovanicaline, 3-hydroxy-4-methoxy-benzaldehyde
PubChem CID 12127
IUPAC Name 3-hydroxy-4-methoxybenzaldehyde
SMILES COC1=C(C=C(C=C1)C=O)O

Specifications

Melting Point 112°C to 116°C
Density 1.2
Boiling Point 179°C (15 mmHg)
Flash Point >110°C (230°F)
Quantity 5 g
Beilstein 1073021
Sensitivity Air and light sensitive
Solubility Information Soluble in acetone and methanol.
Formula Weight 152.15
Percent Purity 98%
Chemical Name or Material 3-Hydroxy-4-methoxybenzaldehyde
Show More Show Less
Hazard Category H315-H319-H335
Hazard Statement GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber 210-694-9
RTECSNumber CU6540000
TSCA Yes
Recommended Storage Ambient temperatures

RUO – Research Use Only

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.