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Medchemexpress LLC 3-Hydroxybutyrate dehydrogenase (3-HBDH) | 9028-38-0 | ≥100 U/mg solid | 100 U
Supplier: Medchemexpress LLC HYP2994100U
3-Hydroxybutyrate dehydrogenase (3-HBDH) is a mitochondrial enzyme that plays a key role in the ketone body metabolism pathway. It functions as the final enzyme for ketone synthesis in the liver and the initial enzyme for ketone breakdown in extracellular tissues. The absence of 3-Hydroxybutyrate dehydrogenase can lead to inhibited fatty acid oxidation in the liver during fasting in mice, resulting in lipid accumulation and the development of fatty liver.
- Mitochondrial enzyme.
- Key enzyme in ketone body metabolism.
- Involved in both ketone synthesis and breakdown.
- Its absence can lead to fatty liver and severe hypoketosis.
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